What is the impact of cannabinoids on skin?

What is the impact of cannabinoids on skin? 

 

The new CBD Lotion extra strength formula contains 2000mg CBG/CBD 1:15 ratio and 15% arnica oil. It also includes the benefits of shea butter and essential oils. What's the difference between sublingually and topically applying cannabinoids? Let's see...

Cannabinoids are available orally, sublingually, or inhaled through a vape pen. Many cosmetic products contain cannabinoids such as CBD. What is the impact of cannabinoids on skin? Can they pass through the protective barrier? Or do their effects penetrate the skin deep below the surface?

Can cannabinoids be absorbed through skin?

Many people believe that cannabinoid enters their bodies when they apply a cream containing cannabinoid to their skin. It is possible to dispute this supposition. It all depends. There are two ways to apply CBD or any other cannabinoids on the skin: topical and transdermal.

Topical application refers to creams or ointments that are applied on the skin's outermost layers. These products target the skin and don't transport cannabinoids below the blood vessels.

Transdermal CBD products on the other side penetrate the skin's top layers and reach the bloodstream. Transdermal CBD gels have been shown increase plasma levels of cannabinoid, making CBD easier to access.

Transdermal CBD does not mean you have to just rub the cannabinoid onto your skin. It takes many adjuvants to make a hydroalcoholic gel which penetrates the epidermis.

Although transdermal cannabinoids are not well studied, this method may be able bypass the digestive system to deliver cannabinoids directly into the bloodstream. This administration method is very similar to sublingual intake. Multiple patents are available for transdermal cannabinoids.

What do cannabinoids do for the skin?

Transdermal delivery can deliver cannabinoids directly to the bloodstream. Topical products offer a distinct advantage. The skin, like many other parts of our bodies, has cannabinoid-receptors. The body's regulator system, the Endocannabinoid (ECS), is important and helps many biological systems maintain homeostasis. The skin is no exception.

A review published Trends In Pharmacological Sciences said that the skin's Endocannabinoid system plays a critical role in many important processes. The structure of external cannabinoids is similar to those found in the body, and they target the same receptors.

Cannabinoids and dermatological issues

Numerous studies have investigated the effects of cannabinoids on dermatological issues. An study that was published in the Journal of Dermatological Science looked at the effects of cannabinoids upon keratinocyte proliferation. This condition is commonly associated with flaky, red skin.

These symptoms can be caused by an immune system attack on healthy skin cells. This is known as a problem with homeostatic regulation. This results in a rapid accumulation skin cells on the skin's surface. CBD, CBN, and THC were shown to reduce keratinocyte production and restore skin balance. More research is still needed to confirm these findings.

Researchers also looked at how cannabinoids affect sebum production. The oily substance can cause the formation of bacteria in pores. Research published Journal of Clinical Investigation. The effects of CBD oil on human serum cells (cells that produce excessive sebum) was the subject of this study. These cells may be helped by CBD oil acting on A2A or TRPV4 receptors, according to researchers.

Conclusion: Cannabinoids are good for skin

Although research is still in its infancy it is clear that cannabinoids have fascinating effects on the skin. After the discovery of ECS, the largest of our organs, many questions have been raised about cannabinoids.